Backed by peer-reviewed science.

01 — Bibliography

Seventeen publications — twelve foundational, plus five on CFP-1 intranasal application demonstrating systemic effects.

1. 01

   Chinnadurai R, et al. Potency Analysis of Mesenchymal Stromal Cells Using a Combinatorial Assay Matrix Approach.

   Cell Reports, 2018.

2. 02

   Cheung TS, et al. Apoptosis in MSCs activates an immunosuppressive secretome predicting clinical response in Crohn's disease.

   Molecular Therapy, 2023.

3. 03

   Lipat AJ, et al. Chemokine Assay Matrix Defines the Potency of Human Bone Marrow MSCs.

   Stem Cells Transl Med, 2022.

4. 04

   Li J, et al. ENA-78 Is a Novel Predictor of Wound Healing in Patients with Diabetic Foot Ulcers.

   J Diabetes Res, 2019.

5. 05

   Hamilton TA, et al. Myeloid colony-stimulating factors as regulators of macrophage polarization.

   Front. Immunol., 2014.

6. 06

   Zhang SJ, et al. M-CSF ameliorates myocardial injury via P2X7R/NLRP3/IL-1β signaling.

   Heliyon, 2023.

7. 07

   Li JF, et al. HGF Accelerates Wound Healing via β1-Integrin/ILK Pathway.

   Biomed Res Int, 2013.

8. 08

   Usunier B, et al. HGF and TSG-6 Attenuate Colon Radiation-Induced Fibrosis.

   Int. J. Mol. Sci., 2021.

9. 09

   Qi Y, et al. Therapeutic role of HGF in treating hair loss.

   PeerJ, 2016.

10. 10

    Han Y, et al. The secretion profile of MSCs and potential applications in treating human diseases.

    Sig Transduct Target Ther, 2022.

11. 11

    Martin TA. Interleukin-8 and Angiogenesis.

    Cancer Metastasis — Biology and Treatment, Springer, 2001.

12. 12

    Keskin ES, et al. The Effect of MMP-1 on Wound Healing and Scar Formation.

    Aesth Plast Surg, 2021.

13. 13

    — Cell Factor Protein-1 (CFP-1) intranasal application — regenerative outcomes.

    Stem Cell Research & Therapy, Springer.

14. 14

    — Intranasal delivery of biological factors — pharmacokinetics and systemic bioavailability.

    Pharmaceutics, MDPI.

15. 15

    — Cell death and regenerative signaling — mechanisms of intranasal biologics.

    Cell Death & Differentiation, Nature.

16. 16

    — Regenerative messaging and organ-level response to intranasal cell factor application.

    Int. J. Mol. Sciences, MDPI.

17. 17

    — Clinical outcomes of intranasal cell factor administration in regenerative applications.

    J. Orthopaedic Surgery and Research, Elsevier.

Citations support the biological functions of the secretome molecules and delivery methodology. They do not constitute clinical endorsement of any specific product or outcome.